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Address: Office: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.
Phone: 203-483-1317; Fax: 203-483-3273.
Home: 3 Kafr Abdu St., Rushdy, Alexandria, EGYPT.
Phone: 203-542-0910, GSM: 2010-170-8625.
E-Mail: yasser_abdel_ghany@hotmail.com
Birth: August 26th, 1959, Alexandria, EGYPT
Education:
1981
B.Sc. of Pharmaceutical Sciences, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.
1985
M.Sc. of Pharmaceutical Sciences, “Pharmaceutical Chemistry” Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.
Thesis Title: Synthesis of Some Thiazolidine Derivatives of Possible Antimicrobial Activity.
1992
PH.D. in Pharmaceutical Sciences, “Medicinal Chemistry”, The Ohio State University, Columbus, Ohio, USA.
Dissertation title: Osmotic Processes as Targets foe Drug Design
Part I: The Polyol Pathway Design and Synthesis of Inhibitors of the Aldose Reductase Enzyme.
Part II: The Bacterial Osmotolerance A Study of the Structural Requirement for the Glycine Betaine-Choline Transport System.
Professional Work Experience:
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1981-1985 |
Instructor,
Practical Pharmaceutical Chemistry, Faculty of Pharmacy,
University of Alexandria, Alexandria,
EGYPT. |
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1985-1987 |
Assistant Lecturer,
Department of Pharmaceutical Chemistry, Faculty of Pharmacy,
University of Alexandria, Alexandria,
EGYPT. |
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1987-1989 |
Egyptian-American Peace Fellowship,
College of Pharmacy, The Ohio State University, Columbus, Ohio,
USA. |
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1989-1990 |
Egyptian Scientific Mission Fellowship,
College of Pharmacy, The Ohio State University, Columbus, Ohio,
USA. |
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1990-1991 |
Graduate Teaching Assistant,
College of Pharmacy, The Ohio State University, Columbus, Ohio,
USA. |
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1991-1992 |
Graduate Research Assistant,
College of Pharmacy, The Ohio State University, Columbus, Ohio,
USA. |
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12/92- 4/93 |
Visiting Assistant Professor,
College of Pharmacy, The Ohio State University, Columbus, Ohio,
USA. |
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5/93-12/96 |
Assistant Professor,
Department of
Pharmaceutical Chemistry, Faculty of Pharmacy, University of
Alexandria, Alexandria,
EGYPT. |
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12/96- 1/97 |
Visiting Assistant Professor,
Faculty of Pharmacy, Beirut Arab University, Beirut,
Lebanon. |
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5/97- 6/97 |
Visiting Assistant Professor,
Faculty of Pharmacy, Beirut Arab University, Beirut,
Lebanon. |
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9/97-9/2001 |
Senior Lecturer,
Department of Pharmaceutical Chemistry & Biochemistry, Oman
Assistant Pharmacy Institute, Ministry of Health, Sultanate of
Oman, Muscat, Sultanate of Oman. |
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1997-2001 |
Training Coordinator,
Oman Assistant Pharmacy Institute, Ministry of Health, Sultanate
of Oman, Muscat, Sultanate of
Oman. |
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9/03-11/03 |
Visiting Assistant Professor,
Faculty of Pharmacy, Beirut Arab University, Beirut,
Lebanon. |
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9/04-11/04 |
Visiting Assistant Professor,
Faculty of Pharmacy, Beirut Arab University, Beirut,
Lebanon. |
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11/05-12/05 |
Visiting Assistant Professor,
Faculty of Pharmacy, Beirut Arab University, Beirut,
Lebanon |
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9/2001-present |
Assistant Professor,
Department of
Pharmaceutical Chemistry, Faculty of Pharmacy, University of
Alexandria, Alexandria,
EGYPT. |
Honors and Professional Affiliations:
1981 B.Sc. in Pharmaceutical Sciences, Magna Cum Laude. 1981-present Member-Egyptian Pharmaceutical Syndicate.
1988-1995 Member-American Chemical Society. 1988-1995 Member-Medicinal Chemistry Division, ACS.
1989-present Member-Rho Chi Pharmaceutical Honor Society. 1989-1995 Member-Organic Chemistry Division, ACS.
1992 PH. D. Pharmaceutical Sciences “Medicinal Chemistry”, Magna Cum Laude.
1993-present Member-Egyptian Pharmaceutical Society.
Invited Speakers: University of Tennessee, Department of Medicinal Chemistry Scientific Seminar Program; February 1993. Lecture Title: “Osmotic Processes As Targets For Drug Design”.
Egyptian National Organization of Quality Control and Drug Research, Programs for Scientific & Technological Development, Scientific & Training Program, First Symposium; December 1993. Lecture Title: “Chirality And Drug Receptor Interactions”.
Ministry of Health, Sultanate of Oman, Continuing Pharmaceutical Education Program, March 1998. Lecture Title: “Strategies Of Antibacterial Chemotherapy”.
Ministry of Health, Sultanate of Oman, Continuing Pharmaceutical Education Program, March 2000. Lecture Title: “Antiviral Therapy, Success and Failure”
Technical Experience:
>Designing and Teaching theoretical and practical Medicinal Chemistry courses at a Graduate and Undergraduate University Level.
>Utilization and operation of advanced spectroscopic techniques in the area of Synthetic Medicinal Chemistry research including FT-IR, FT-NMR, MS, HPLC and GC.
>Hands on experience in the utilization of Radioactive Isotopes and Radioactive Synthesis in the field of Bio-organic and Medicinal Chemistry.
>Utilization of Personal Computers, Main Frames and Work Stations in the field of Computer Aided Drug Design.
>Hands on Experience in managing and running a Public Retail Pharmacy.
>Designing and coordinating the Field Pharmacy Training Courses in the Pharmacy Departments of Governmental Referral Hospitals, Health Complexes, Health Centers in addition to Private Retail Pharmacies.
References:
Prof. Dr. Mahmoud Mohy-Eldin
Professor of Pharmacology, Dean, Faculty of Pharmacy,University of Alexandria, Alexandria, EGYPT
Prof. Dr. Fawzy El-Yazbi
Professor of Pharmaceutical Analytical Chemistry, Dean, College of Pharmacy, Beirut Arab University, Beirut, Lebanon
Prof. Dr. Robert W. Brueggmeier
Professor of Medicinal Chemistry, Dean, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.
Prof. Dr. Duane D. Miller
Professor of Medicinal Chemistry, Department of Medicinal Chemistry, University of Tennessee at Memphis, Memphis, Tennessee, USA
Publications & Abstracts:
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1. |
Rida, S. M.; Salama, H. M.;
Labouta, I.M.; A.-Ghany, Y. S. Synthesis of some
3-(Benzimidazol-2-ylmethyl)Thiazolidinone Derivatives as
Potential Antimicrobial Agents Pharmazie
1985, 40, 727-728.
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2. |
Rida, S. M.; Salama, H. M.;
Labouta, I.M.; A.-Ghany, Y. S. Synthesis and In
Vitro Antimicrobial Activities of
Thiazolo[3,2-a]benzimidazol-3(2H)-ones Pharmazie
1986, 41, 324-326.
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3. |
Rida, S. M.; Salama, H. M.;
Labouta, I.M.; A.-Ghany, Y. S.; El-Ghazzaui, E.; Kader,
O. Synthesis and In Vitro Antimicrobial Evaluation of
some Benzimidazol-2-ylmethylthioureas,
Benzimidazol-2-ylmethylthiosemicarbazides and Products of their
Condensation with Monochloroacetic Acid Pharmazie
1986, 41, 475-478.
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4. |
Miller, D. D.; Abdel-Ghany, Y.
S.; Donkor, I.; Kador, P.F.; Mizoguchi, T. Chemoreactive
Alrestatin Analogs as Possible Irreversible Inhibitors of Aldose
Reductase US-Japan Aldose Reductase Workshop,
Kona, Hawaii, February 1991.
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5. |
Abdel-Ghany, Y. S.;
Donkor, I.; Kador, P. F.; Mizoguchi, T.; Malik, A.; Miller, D.
D. Novel
Alrestatin Analogs with Potent Reversible and Irreversible
Inhibitory Activity for the Enzyme Aldose Reductase 203rd
American Chemical Society National Meeting, San
Francisco, California, April 1992, Abst. No. 135.
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6. |
Abdel-Ghany, Y. S.;
Miller, D. D.; Inhat, M.; Kunin, C.; Tong, H. Glycine Betaine
and Choline Transport Systems as Possible Routes of Delivering
Cytotoxic Analogs into the Enteric Bacteria 25th
Annual Graduate Student Meeting in Medicinal Chemistry,
Ann Arbor, Michigan, June 1992.
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7. |
Abdel-Ghany, Y. S.;
Inhat, M.; Miller, D.D.; Kunin, C.M.; Tong, H. H. Structure
Activity Relationship of Glycine Betaine analogs on
Osmotolerance of Enteric Bacteria J. Med.Chem.
1993, 32, 784-787.
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8. |
Kunin, C. M.; Tong, H. H.;
Miller, D. D.; Abdel-Ghany, Y. S.; Poggi, M.-C.;
LeRudulier, D. Effect of Novel Compound,
I-Methyl-1-Pieperidino-Methane Sulfonate (MPMS), on the
Osmoprotectant Activity of Glycine Betaine, Choline and
L-proline in Escherichia coli Arch Microbiol.
1993, 160, 81-86.
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9. |
Abdel-Ghany, Y. S.
; Miller, D. D. ; Kunin, C.; Tong, H.; Inhat, M. Bacterial
Osmoadaptation Mechanisms as Targets for Drug Design 205th
American Chemical Society National Meetings, Denver,
Colorado, March 1993, Abst. No. 61.
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10. |
Kador, P. F.; Lee, Y. S.;
Rodriguez, L. ; Sato, S. ; Bratoszko, A. M.; Abdel-Ghany, Y.
S.; Miller, D. D. Identification of an Aldose Reductase
Inhibitor Site by Affinity Labeling Bioorg. Med. Chem.
1995, 3, 1313-24.
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11. |
Chaaban, I.; Bekhit, A. A.; Abdel-Ghany, Y. S.
Synthesis of Novel Benzoquinone and Hydroquinone Derivatives
Bearing Different Heterocyclic Systems as Potential
Antimicrobial Agents
Egypt. J.
Pharm. Sci.
1998, 39, 91-107.
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12. |
Donkor, IO, Abdel-Ghany, YS,
Mizoguchi, T., Kador, P., Miller, D.D., Synthesis and Biological
Activities of Aldose Reductase Inhibitors Bearing Acyl
Benzenesulfonamide As Carboxylic Acid Surrogates Eur J.
Med. Chem. 1998 33,15-22.
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13. |
Donkor, I. O.; Abdel-Ghany, Y. S.; Kador, P. F.;
Mizoguchi, T.; Malik, A. B. ; Miller, D. D. Synthesis and
Biological
Activity of Aldose Reductase Inhibitors with
Michael Acceptor Substituents Eur. J. Med.Chem.
1999, 34, 235-243.
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14 |
Bekhit A. A., Chaaban I., Abdel-Ghany Y. S.,
Synthesis of 2,5-Disubstituted-1,4-Benzoquinone Derivatives as
Potential Antimicrobial Agents, Proceedings of Assiut
University 2nd Pharmaceutical Sciences Conference,
2000, 8-9 March, pp.107-114.
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