Dr. Yasser Saad Abdel Ghany



Address:
Office: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.
Phone: 203-483-1317; Fax: 203-483-3273.

Home: 3 Kafr Abdu St., Rushdy, Alexandria, EGYPT.
Phone: 203-542-0910, GSM: 2010-170-8625.

E-Mail: yasser_abdel_ghany@hotmail.com

Birth: August 26th, 1959, Alexandria, EGYPT

Education:
1981 B.Sc. of Pharmaceutical Sciences, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.

1985 M.Sc. of Pharmaceutical Sciences, “Pharmaceutical Chemistry” Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.
Thesis Title: Synthesis of Some Thiazolidine Derivatives of Possible Antimicrobial Activity.

1992 PH.D. in Pharmaceutical Sciences, “Medicinal Chemistry”, The Ohio State University, Columbus, Ohio, USA.
Dissertation title: Osmotic Processes as Targets foe Drug Design
Part I: The Polyol Pathway
Design and Synthesis of Inhibitors of the Aldose Reductase Enzyme.
Part II: The Bacterial Osmotolerance
A Study of the Structural Requirement for the Glycine Betaine-Choline Transport System.

Professional Work Experience:

1981-1985

Instructor, Practical Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.

1985-1987

Assistant Lecturer, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.

1987-1989

Egyptian-American Peace Fellowship, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

1989-1990

Egyptian Scientific Mission Fellowship, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

1990-1991

Graduate Teaching Assistant, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

1991-1992

Graduate Research Assistant, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

12/92- 4/93

Visiting Assistant Professor, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

5/93-12/96

Assistant Professor, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.

12/96- 1/97

Visiting Assistant Professor, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon.

5/97- 6/97

Visiting Assistant Professor, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon.

9/97-9/2001

Senior Lecturer, Department of Pharmaceutical Chemistry & Biochemistry, Oman Assistant Pharmacy Institute, Ministry of Health, Sultanate of Oman, Muscat, Sultanate of Oman.

1997-2001

Training Coordinator, Oman Assistant Pharmacy Institute, Ministry of Health, Sultanate of Oman, Muscat, Sultanate of Oman.

9/03-11/03

Visiting Assistant Professor, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon.

9/04-11/04

Visiting Assistant Professor, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon.

11/05-12/05

Visiting Assistant Professor, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon

9/2001-present

Assistant Professor, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, EGYPT.


Honors and Professional Affiliations:
1981 B.Sc. in Pharmaceutical Sciences, Magna Cum Laude.
1981-present Member-Egyptian Pharmaceutical Syndicate.
1988-1995 Member-American Chemical Society.
1988-1995 Member-Medicinal Chemistry Division, ACS.
1989-present Member-Rho Chi Pharmaceutical Honor Society.
1989-1995 Member-Organic Chemistry Division, ACS.
1992 PH. D. Pharmaceutical Sciences “Medicinal Chemistry”, Magna Cum Laude.
1993-present Member-Egyptian Pharmaceutical Society.

Invited Speakers:
University of Tennessee, Department of Medicinal Chemistry Scientific Seminar Program; February 1993.
Lecture Title: “Osmotic Processes As Targets For Drug Design”.

Egyptian National Organization of Quality Control and Drug Research, Programs for Scientific & Technological Development, Scientific & Training Program, First Symposium; December 1993.
Lecture Title: “Chirality And Drug Receptor Interactions”.

Ministry of Health, Sultanate of Oman, Continuing Pharmaceutical Education Program, March 1998.
Lecture Title: “Strategies Of Antibacterial Chemotherapy”.

Ministry of Health, Sultanate of Oman, Continuing Pharmaceutical Education Program, March 2000.
Lecture Title: “Antiviral Therapy, Success and Failure”

Technical Experience:
>Designing and Teaching theoretical and practical Medicinal Chemistry courses at a Graduate and Undergraduate University Level.
>Utilization and operation of advanced spectroscopic techniques in the area of Synthetic Medicinal Chemistry research including FT-IR, FT-NMR, MS, HPLC and GC.
>Hands on experience in the utilization of Radioactive Isotopes and Radioactive Synthesis in the field of Bio-organic and Medicinal Chemistry.
>Utilization of Personal Computers, Main Frames and Work Stations in the field of Computer Aided Drug Design.
>Hands on Experience in managing and running a Public Retail Pharmacy.
>Designing and coordinating the Field Pharmacy Training Courses in the Pharmacy Departments of Governmental Referral Hospitals, Health Complexes, Health Centers in addition to Private Retail Pharmacies.

References:
Prof. Dr. Mahmoud Mohy-Eldin
Professor of Pharmacology, Dean, Faculty of Pharmacy,University of Alexandria, Alexandria, EGYPT

Prof. Dr. Fawzy El-Yazbi
Professor of Pharmaceutical Analytical Chemistry, Dean, College of Pharmacy, Beirut Arab University, Beirut, Lebanon

Prof. Dr. Robert W. Brueggmeier
Professor of Medicinal Chemistry, Dean, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

Prof. Dr. Duane D. Miller
Professor of Medicinal Chemistry, Department of Medicinal Chemistry, University of Tennessee at Memphis, Memphis, Tennessee, USA

Publications & Abstracts:

1.

Rida, S. M.; Salama, H. M.; Labouta, I.M.; A.-Ghany, Y. S.   Synthesis of some 3-(Benzimidazol-2-ylmethyl)Thiazolidinone Derivatives as Potential Antimicrobial Agents   Pharmazie  1985, 40, 727-728.

 

2.

Rida, S. M.; Salama, H. M.; Labouta, I.M.; A.-Ghany, Y. S.   Synthesis and In Vitro Antimicrobial Activities of Thiazolo[3,2-a]benzimidazol-3(2H)-ones   Pharmazie  1986, 41, 324-326.

 

3.

Rida, S. M.; Salama, H. M.; Labouta, I.M.; A.-Ghany, Y. S.; El-Ghazzaui, E.; Kader, O.   Synthesis and In Vitro Antimicrobial Evaluation of some Benzimidazol-2-ylmethylthioureas, Benzimidazol-2-ylmethylthiosemicarbazides and Products of their Condensation with Monochloroacetic Acid  Pharmazie  1986, 41, 475-478.

 

4.

Miller, D. D.; Abdel-Ghany, Y. S.; Donkor, I.; Kador, P.F.; Mizoguchi, T.   Chemoreactive Alrestatin Analogs as Possible Irreversible Inhibitors of Aldose Reductase  US-Japan Aldose Reductase Workshop, Kona, Hawaii, February 1991.

 

5.

Abdel-Ghany, Y. S.; Donkor, I.; Kador, P. F.; Mizoguchi, T.; Malik, A.; Miller, D. D.   Novel Alrestatin Analogs with Potent Reversible and Irreversible Inhibitory Activity for the Enzyme Aldose Reductase   203rd American Chemical Society National Meeting, San Francisco, California, April 1992, Abst. No. 135.

 

6.

Abdel-Ghany, Y. S.; Miller, D. D.; Inhat, M.; Kunin, C.; Tong, H.   Glycine Betaine and Choline Transport Systems as Possible Routes of Delivering Cytotoxic Analogs into the Enteric Bacteria   25th Annual Graduate Student Meeting in Medicinal Chemistry, Ann Arbor, Michigan, June 1992.

 

7.

Abdel-Ghany, Y. S.; Inhat, M.; Miller, D.D.; Kunin, C.M.; Tong, H. H.   Structure Activity Relationship of Glycine Betaine analogs on Osmotolerance of Enteric Bacteria   J. Med.Chem. 1993, 32, 784-787.

 

8.

Kunin, C. M.; Tong, H. H.; Miller, D. D.; Abdel-Ghany, Y. S.; Poggi, M.-C.; LeRudulier, D.   Effect of Novel Compound, I-Methyl-1-Pieperidino-Methane Sulfonate (MPMS), on the Osmoprotectant Activity of Glycine Betaine, Choline and L-proline in Escherichia coli   Arch Microbiol. 1993, 160, 81-86.

 

9.

Abdel-Ghany, Y. S. ; Miller, D. D. ; Kunin, C.; Tong, H.; Inhat, M.   Bacterial Osmoadaptation Mechanisms as Targets for Drug Design   205th American Chemical Society National Meetings, Denver, Colorado, March  1993, Abst. No. 61.

 

10.

Kador, P. F.; Lee, Y. S.; Rodriguez, L. ; Sato, S. ; Bratoszko, A. M.; Abdel-Ghany, Y. S.; Miller, D. D.   Identification of an Aldose Reductase Inhibitor Site by Affinity Labeling   Bioorg. Med. Chem1995, 3, 1313-24.

 

11.

Chaaban, I.; Bekhit, A. A.; Abdel-Ghany, Y. S.   Synthesis of Novel Benzoquinone and Hydroquinone Derivatives Bearing Different Heterocyclic Systems as Potential Antimicrobial Agents   Egypt. J. Pharm. Sci1998, 39, 91-107.

 

12.

Donkor, IO, Abdel-Ghany, YS, Mizoguchi, T., Kador, P., Miller, D.D., Synthesis and Biological Activities of Aldose Reductase Inhibitors Bearing Acyl Benzenesulfonamide As Carboxylic Acid Surrogates   Eur J. Med. Chem. 1998  33,15-22.

 

13.

Donkor, I. O.; Abdel-Ghany, Y. S.; Kador, P. F.; Mizoguchi, T.; Malik, A. B. ; Miller, D. D.   Synthesis and Biological Activity of Aldose Reductase Inhibitors with Michael Acceptor Substituents   Eur. J. Med.Chem.   1999, 34, 235-243.

 

14

Bekhit A. A., Chaaban I., Abdel-Ghany Y. S., Synthesis of 2,5-Disubstituted-1,4-Benzoquinone Derivatives as Potential Antimicrobial Agents, Proceedings of Assiut University 2nd Pharmaceutical Sciences Conference, 2000, 8-9 March, pp.107-114.

 


Copyright © 2006 Faculty of Pharmacy, Alexandria University, Egypt.
All rights reserved.