Prof. Dr. Mahmoud Mohamed Elmas




Current position:

Mahmoud Mohamed El-Mas, M.S., Ph.D.

Professor

Department of Pharmacology, Faculty of Pharmacy

University of Alexandria , Alexandria , Egypt

Tel: (+203)523-3926; (+2010)170-8620 (mobile)

Fax: (+203)487-3273, Email: mahelm@hotmail.com



Date & Place of Birth: January 6, 1960, Egypt

Qualifications:  
  1. B.S., Pharmacy with the grade of Distinction Honor (1982), Faculty of Pharmacy, Univ. of Alexandria , Egypt .

  2.  M.S., Pharmacology (1986) entitled "Comparative study of some drugs used in treatment of experimental gastric ulceration". Dept. of Pharmacology, Faculty of Pharmacy, Univ. of Alexandria , Egypt.

  3. Ph.D., Pharmacology (1990) entitled "An investigation of the relationship between presynaptic a-adrenoceptors, uptake mechanism and the control of noradrenaline release", under the joint supervision of the Dept. of Pharmacology, School of Medicine, Univ. of Leeds, England, and the Dept. of Pharmacology, Faculty of Pharmacy, Univ. of Alexandria, Egypt.

Career History:

1. Instructor (1982-1990), Dept. of Pharmacology, Faculty of Pharmacy, Univ. of Alexandria , Egypt .

2. Assistant Professor (1990-1995), Dept. of Pharmacology, Faculty of Pharmacy, Univ. of Alexandria , Egypt .

3.  Associate Professor (1995-2000), Dept. of Pharmacology, Faculty of Pharmacy, Univ. of Alexandria , Egypt .

4.  Professor (2000-present), Dept. of Pharmacology, Faculty of Pharmacy, Univ. of Alexandria , Egypt .

Academic and Research Experience Abroad:
1. Full-time Ph.D. Student (1988-1990), Dept. of Pharmacology, School of Medicine, Univ. of Leeds, U.K. according to the Ph.D. joint supervision scheme between Egypt and foreign countries.
2. Visiting Professor, Dept. of Pharmacology and Toxicology, School of Medicine, East Carolina Univ., Greenville, NC 27858, U.S.A, for a total of 9 years during the following time periods:

 Jan 1991-Jan 1993

Jun-Aug 1993

Jan 1996-Jun 1999

Sep-Dec 2000

Apr 2002-Dec 2004

Jul-Oct 2005

Aug-Dec 2006

Teaching Experience:
• Teaching Pharmacology and Toxicology to undergraduate pharmacy students.
• Teaching advanced courses of Pharmacology and Toxicology to graduate students and guiding their research projects.
• Lecturing in the "Continuing Education Program" organized by the Egyptian Syndicate of Pharmacists and aimed at delivering recent drug developments and technologies to clinical, hospital, and retail Pharmacists.

Scientific consultations and Committees:

  • Scientific Consultant (1994-1995), PHARCO Pharmaceutical Co., Alexandria, Egypt.

  • Member (2001-2002), Committee on Environment and Community Development, Faculty of Pharmacy, University of Alexandria, Egypt.

  • Member (2005-2006), Committee on Education and Student affairs, Faculty of Pharmacy, University of Alexandria, Egypt

  • A recognized reviewer for top international scientific journals (e.g. J Pharmacol Exp Ther, Am J Physiol, J Appl Physiol, Biochem Pharmacol, Cardiovasc Drugs Ther, …..etc).

  • Editorial Board Member: Pharmacy Times Middle East.

  • Regional Editor: American Journal of Food Technology, International Journal of Pharmacology, and Journal of Pharmacology and Toxicology.

Awards, Honors, and Grants:

  1. Alexandria University Student Union's Award for scientific distinction (1980).

  2. Egyptian Pharmaceutical Companies' Award for top graduate in pharmaceutical sciences (1982).

  3. American Heart Association Grant (1992-1993; #NC-92-GB-4) "Functional interaction between aortic baroreceptors and central a2-adrenergic and imidazole receptors".

  4. Biomedical Research Support Grant from the School of Medicine, East Carolina University, North Carolina, U.S.A. (1992-1993) "Role of glutamate receptors in the depressant effect of ethanol on baroreflexes".

  5. The State Prize for Scientific Encouragement in Medical Sciences (1994, 2000), awarded by the Egyptian Academy of Scientific Research and Technology, The General Directorate for National Prizes in Egypt.

  6. The State Prize for Scientific Excellence in Medical Sciences (2006), awarded by the Egyptian Academy of Scientific Research and Technology, The General Directorate for National Prizes in Egypt.

  7. The Egyptian General Syndicate of Pharmacists’ Awards (Silver and Gold Medals) for professional and scientific accomplishments (2002, 2006).

  8. Biography enlisted in the “Marquis Who’sWho in Medicine and Healthcare”, 6th Edition (2006/2007), pp. 356.

Research Interests:

  • Cardiovascular neurobiology and hemodynamics that pertain to peripheral and central mechanisms involved in arterial pressure regulation. More specifically, the interactions of alcohol (ethanol) or immunosuppressant drugs with circulatory and renal controlling mechanisms and antihypertensive medications and the gender specificity of these effects. Integrative, cellular, and molecular mechanisms involved in the hemodynamic effects of alcohol and its deleterious interactions with arterial baroreflexes and antihypertensive medications including phosphatidylcholine-phosphlipase C, mitogen-activated protein kinase (MAPK), nitric oxide synthases, and immediate early genes (transcription regulating factors).

  • Signaling pathways involved in the modulation by vascular endothelium of vascular tone and pre- and post-synaptic regulatory mechanisms of neurotransmission at vascular and non-vascular sites.

Methodologies and techniques:
• Invasive and non-invasive methods for measurement of arterial pressure in conscious animals: direct vascular cannulation, tail cuff technique, and radiotelemetry.
• Thermodilution technique for measurement of cardiac output and its derivatives (stroke volume and vascular resistance).
• Microdialysis of body fluids (e.g. blood, cerebrospinal fluid).
• Stereotaxic techniques for central drug microinjection.
• Receptor autoradiographic binding studies.
• In-vivo electrochemistry for measurment of levels of monoamines in specific brain areas.
• In-situ hybridization and gene expression.
• Surgical deafferentation of arterial baroreceptors.
• Electrical nerve stimulation (aortic depressor, vagal, etc).
• Electrical-field stimulation (neurotrasmitter release studies).
• Recording isometric contractions from cardiac and vascular and non-vascular smooth muscle preparations.
• HPLC & applications
• Gonadectomy

Conferences Attended:

  1. Egyptian Society of Pharmacology and Experimental Therapeutics, March 1985, Alexandria, Egypt.

  2. British Pharmacological Society, September 1988, Nottingham, U.K.

  3. British Pharmacological Society, July 1989, Leeds, U.K.

  4. British Pharmacological Society, January 1990, London, U.K.

  5. American Society of Pharmacology and Experimental Therapeutics, August 1992, Orlando, Florida, U.S.A.

  6. Egyptian Society of Pharmacology and Experimental Therapeutics, February 1994, Cairo, Egypt.

  7. In Situ Polymerase Chain Reaction Symposium, March 1996, Research Triangle Park, North Caroline, U.S.A.

  8. Experimental Biology, April 1997, New Orleans, Louisiana, U.S.A.

  9. Experimental Biology, April 1998, San Francisco, California, U.S.A.

  10. American Heart Association, November 1998, Dallas, Texas, U.S.A.

  11. Experimental Biology, April 1999, Washington D.C., U.S.A.

  12. Egyptian Society of Toxicology, October 1999, Alexandria, Egypt.

  13. Principles of Genetic Engineering Workshop, February 2000, Institute of Graduate Studies and Research, Alexandria, Egypt.

  14. Experimental Biology, April 2003, San Diego, California, U.S.A.

  15. Experimental Biology, April 2004, Washington D.C., U.S.A.

  16. BioVision Alexandria, April 2006, Alexandria, Egypt.

Publications:
(A) Full-length research papers
A total of 62 articles of which 56 are published in international peer-reviewed journals
1. Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A and Zeitoun R (1987). Effects of andursil, ranitidine and prostaglandin E2 on indomethacin induced gastric ulcers in the rat. Bull Alex Fac Med, XXIII 1, 69-78.
2. Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A. and Zeitoun R (1987). Protective effect of hyoscine against stress and indomethacin induced gastric ulcers in the rat. Bull Alex Fac Med, XXIII 1, 93-101.
3. Rashida Z, Abou Zeit-Har MS, Bistawroos AE, El-Mas MM and Ghazal A (1987). Synergistic effect of combined antacid and ranitidine treatment on restraint induced gastric ulcers in the rat. Bull Alex Fac Med, XXIII 1, 79-91.
4. El-Mas M, Goodall J and Hughes IE (1989). On the mechanism involved in the ability of meptazinol to potentiate the effects of sympathetic nerve stimulation. J Pharm Pharmacol 41, 242-246.
5. El-Mas M and Hughes IE (1990): Effect of blockade of noradrenaline re-uptake on evoked tritium overflow from mouse vasa deferentia and rat cortex slices. Br J Pharmacol 101, 762-768.
6. Bedwell AM, El-Mas M and Hughes IE (1992). Effect of cocaine on tritium overflow evoked from vasa deferentia previously loaded with [3H]noradrenaline by stimulation using different types of electrodes. J Pharm Pharmacol 44, 235-238.
7. El-Mas MM and Abdel-Rahman AA (1992). Role of aortic baroreceptors in ethanol-induced impairment of baroreflex control of heart rate in conscious rats. J Pharmacol Exp Ther 262, 157-165.
8. Abdel-Rahman AA, Carroll RG and El-Mas MM (1992). Role of the sympathetic nervous sysem in alcohol-guanabenz hemodynamic interaction. Can J Physiol Pharmacol 70, 1217-1224.
9. El-Mas MM and Abdel-Rahman AA (1993). Direct evidence for selective involvement of aortic baroreceptors in ethanol-induced impairment of baroreflex control of heart rate. J Pharmacol Exp Ther 264, 1198-1205.
10. El-Mas MM and Abdel-Rahman AA (1993). Role of NMDA and non-NMDA receptors in the nucleus tractus solitarius in the depressant effect of ethanol on baroreflexes. J Pharmacol Exp Ther 266, 602-610.
11. El-Mas MM, Carroll RG and Abdel-Rahman AA (1993). Blood pressure normalization in carotid barodenervated rats: role of cardiac output. Can J Physiol Pharmacol 71, 783-790.
12. El-Mas MM, Tao S, Carroll RG and Abdel-Rahman AA (1994). Ethanol-clonidine hemodyamic interaction in normotensive rats is modified by anesthesia. Alcohol 11, 307-314.
13. Fahim M, El-Mas MM, Abdel-Rahman AA and Mustafa SJ (1994). Influence of aortic baroreceptor denervation on adenosine receptor-mediated relaxation of isolated rat aorta. Eur J Pharmacol 254, 183-191.
14. El-Mas MM (1994). Influence of anesthesia on baroreflex-mediated control of heart rate. Alex J Pharm Sci 8, 99-104.
15. El-Mas MM, Carroll RG and Abdel-Rahman AA (1994). Centrally-mediated reduction in cariac output elicits the enhanced hypotensive effect of clonidine in conscious aortic barodenervated rats. J Cardiovasc Pharmacol 24, 184-193.
16. El-Mas MM (1995). Oral and injectable hormonal contraceptives in association with breast cancer. Alex J Pharm Sci 9, 75-78.
17. El-Mas MM and Abdel-Rahman AA (1995). Upregulation of imidazoline receptors in the meulla oblongata accounts for the enhanced hypotensive effect of clonidine in aortic baroenervated rats. Brain Res 691, 195-204.
18. Elmallah AI, Sharabi F, Omar AG and El-Mas MM (1995). Prazosin-induced blockade of extraneuronal uptake facilitates dopaminergic modulation of muscle twitches in rat vas deferns. J Pharm Pharmacol 47, 932-936.
19. El-Mas MM and Abdel-Rahman AA (1997). Contrasting effects of urethane, ketamine and thiopental anesthesia on ethanol-clonidine hemodynamic interaction. Alcohol Clin Exp Res 21, 19-27.
20. El-Mas MM, Abdel-Galil AA, El-Gowelli HM and Daabees TT (1997). Short-term aortic barodenervation diminishes a1-adrenoceptor reactivity in rat aortic smooth muscle. Eur J Pharmacol 322, 201-210.
21. El-Mas MM and Abdel-Rahman AA (1997). Aortic barodenervation upregulates a2-adrenoceptors in the nucleus tractus solitarius and rostral ventrolateral medulla: an autoradiographic study. Neuroscience 79, 581-590.
22. El-Mas MM and Abdel-Rahman AA (1997). Role of cardiac output in ethanol-evoked attenuaion of centrally-mediated hypotension in conscious rats. Hypertension 30, 288-294.
23. El-Mas MM, Daabees TT, El-Gowelli HM and Abdel-Galil AA (1997). Enhanced endothelial nitric oxide activity contributes to the reduced responsiveness of vascular a1-adrenoceptors following aortic barodenervation. Eur J Pharmacol 337, 235-243.
24. El-Mas MM (1998). Facilitation of reflex bradycardia does not contribute to the enhanced hypotensive effect of clonidine in aortic barodenervated rats. J Cardiovasc Pharmacol 31, 869-875.
25. El-Mas MM and Abdel-Rahman AA (1998). Ovariectomy abolishes ethanol-induced impairment of baroreflex control of heart rate in conscious rats. Eur J Pharmacol 349, 253-261.
26. El-Mas MM and Abdel-Rahman AA (1998). Ethanol selectively counteracts hypotension evoked via central I1-imidazoline but not a2-adrenergic receptor activation in spontaneously hypertensive rats. J Cardiovasc Pharmacol 32, 382-389.
27. El-Mas MM and Abdel-Rahman AA (1998). Estrogen enhances baroreflex control of heart rate in conscious ovariectomized rats. Can J Physiol Pharmacol 76, 381-386.
28. El-Mas MM and Abdel-Rahman AA (1999). Ethanol counteraction of I1-imidazoline but not alpha-2 adrenergic receptor-mediated reduction in vascular resistance in conscious spontaneously hypertensive rats. J Pharmacol Exp Ther 288, 455-462.
29. El-Mas MM and Abdel-Rahman AA (1999). Acute hemodynamic effects of ethanol in conscious spontaneously hypertensive and normotensive rats. Alcohol Clin Exp Res 23, 285-292.
30. El-Mas MM, Elmallah AI, Omar AG and Sharabi F (1999). Dopamine modulates peripheral purinergic neurotransmission through multiple presynaptic receptors: tissue-dependent effects. Pharmacol Res 39, 11-19.
31. El-Mas MM (1999). Ethanol abolishes clonidine-induced impairment of baroreflex control of heart rate in conscious rats. Gen Pharmacol 32, 207-214.
32. Mohamed MK, El-Mas MM and Abdel-Rahman AA (1999). Estrogen enhancement of baroreflex sensitivity is centrally mediated. Am J Physiol 276, 45, R1030-R1037.
33. El-Mas MM and Abdel-Rahman AA (1999). Estrogen-dependent hypotensive effects of ethanol in conscious female rats. Alcohol Clin Exp Res 23, 624-632.
34. Abdel-Kreem MFM and El-Mas MM (1999). Benzene-1,4-bis [1-(substituted phenethylamino)-cyclohexanes]: potential a2-adrenoceptor probes. Alex J Pharm Sci 13, 47-52.
35. El-Mas MM and Abdel-Rahman AA (1999). Sexually dimorphic hemodynamic effects of intragastric ethanol in conscious rats. Clin Exp Hypertens 21, 1429-1445.
36. El-Mas MM and Abdel-Rahman AA (1999). Role of the sympathetic control of vascular resistance in ethanol-clonidine hemodynamic interaction in SHRs. J Cardiovasc Pharmacol 34, 589-596.
37. El-Mas MM and Abdel-Rahman AA (2000). Ovariectomy alters the chronic hemodynamic and sympathetic effects of ethanol in radiotelemetered female rats. Clin Exp Hypertens 22, 109-126.
38. El-Mas MM and Abdel-Rahman AA (2000). Radiotelemetric evaluation of the hemodynamic effects of long-term ethanol in spontaneously hypertensive and Wistar-Kyoto rats. J Pharmacol Exp Ther 292, 944-951.
39. El-Mas MM and Abdel-Rahman AA (2000). Clonidine diminishes c-jun gene expression in the cardiovascular sensitive areas of the rat brainstem. Brain Res 856, 245-249
40. Zhang J, El-Mas MM and Abdel-Rahman AA (2001). Imidazoline I1 receptor-induced activation of phosphatidylcholine specific phospholipase C elicits mitogen activated protein kinase phosphorylation in PC12 cells . Eur J Pharmacol 415, 117-125.
41. El-Mas MM and Abdel-Rahman AA (2001). Evidence for the involvement of central I1-imidazoline receptor in ethanol counteraction of clonidine hypotension in spontaneously hypertensive rats. J Cardiovasc Pharmacol 38, 417-426.
42. El-Mas MM, Abdel-Rahman AA (2001). Effect of long-term ethanol feeding on brainstem a2-receptor binding in Wistar-Kyoto and spontaneously hypertensive rats. Brain Res 900, 324-328.
43. El-Mas MM and Abdel-Rahman AA (2001). An association between the estrogen-dependent hypotensive effect of ethanol and an elevated brainstem c-jun mRNA in female rats. Brain Res 912, 79-88.
44. El-Mas MM, Afify EA, Mohy El-Din MM, Omar AG and Sharabi FM (2001). Testosterone facilitates the baroreceptor control of reflex bradycardia: role of cardiac sympathetic and parasympathetic components. J Cardiovasc Pharmacol 38, 754-763.
45. El-Mas MM, Afify EA, Omar AG and Sharabi FM (2002). Cyclosporine adversely affects baroreflexes via inhibition of testosterone modulation of cardiac vagal control. J Pharmacol Exp Ther 301, 346-354.
46. El-Mas MM, Afify EA, Omar AG and Sharabi FM (2002). Cyclosporine attenuates the autonomic modulation of reflex chronotropic responses in conscious rats. Can J Physiol Pharmacol 80, 766-776.
47. Rekik M, El-Mas MM, Mustafa SJ, and Abdel-Rahman AA (2002). Role of endothelial adenosine receptor-mediated vasorelaxation in ethanol-induced hypotension in hypertensive rats. Eur J Pharmacol 452, 205-214.
48. El-Mas MM, Afify EA, Omar AG, Mohy El-Din MM, and Sharabi FM (2003). Testosterone depletion contributes to cyclosporine-induced chronic impairment of acetylcholine renovascular relaxations. Eur J Pharmacol 468, 217-224.
49. El-Mas MM and Abdel-Rahman AA (2003). Effects of chronic ethanol feeding on clonidine-evoked reductions in blood pressure, heart rate, and their variability: Time-domain analyses. J Pharmacol Exp Ther 306, 271-278.
50. El-Mas MM, Rekik M, Abdel-Rahman AA, and Mustafa JS (2003). Chronic ethanol feeding potentiates α1-adrenoceptor responsiveness in SHR aortas. Clin Exp Hypertens 25, 381-393.
51. El-Mas MM and Abdel-Rahman AA (2004). Chronic ethanol attenuates I1- or α2-receptor-mediated reductions in blood pressure and hemodynamic variability in hypertensive rats. Eur J Pharmacol 485, 251-262.
52. El-Mas MM, Mohy El-Din MM, El-gowilly SM and Sharabi FM (2004). Relative roles of endothelial relaxing factors in cyclosporine-induced impairment of cholinergic and β-adrenergic renal vasodilations. Eur J Pharmacol 487, 149-158.
53. El-Mas MM, Mohy El-Din MM, El-gowilly SM and Sharabi FM (2004). Regional and endothelial differences in the cyclosporine attenuation of adenosine receptor-mediated vasorelaxations. J Cardiovasc Pharmacol 43, 562-573.
54. El-Mas MM and Abdel-Rahman AA (2004). Effects of long-term ovariectomy and estrogen replacement on clonidine-evoked reductions in blood pressure and hemodynamic variability. J Cardiovasc Pharmacol 43, 607-615.
55. El-Mas MM and Abdel-Rahman AA (2004). Contrasting effects of chronic ethanol feeding on centrally- and peripherally-evoked hypotension in telemetered female rats. Vascul Pharmacol 41, 59-66.
56. El-Mas MM and Abdel-Rahman AA (2004). Differential modulation by estrogen of α2-adrenergic and I1-imidazoline receptor-mediated hypotension in female rats. J Appl Physiol 97, 1237-1244.
57. El-Mas MM and Abdel-Rahman AA (2004). Chronic ethanol-clonidine hemodynamic interaction in telemetered spontaneously hypertensive rats. Vascul Pharmacol 41, 107-113.
58. Omar AG and El-Mas MM (2004). Time-domain evaluation of cyclosporine interaction with hemodynamic variability. Cardiovasc Drugs Therapy, 18, 461-468
59. El-Mas MM and Abdel-Rahman AA (2005). Longitudinal studies on the effect of hypertension on circadian hemodynamic and autonomic rhythms in telemetered rats. Life Sci 76, 901–915.
60. El-Mas MM and Abdel-Rahman AA (2005). Autonomic modulation of altered diurnal hemodynamic profiles in ethanol-fed hypertensive rats. Alcohol Clin Exp Res 29, 499-508.
61. El-Mas MM, Mohy El-Din MM, El-gowilly SM and Sharabi FM (2005). The α1-adrenergic receptor not DA1-dopaminergic receptor mediates cyclosporine-SKF38393 renovascular interaction. Can J Physiol Pharmacol 83, 1129-1136.
62. El-Mas MM, Zhang J and Abdel-Rahman AA (2006). Upregulation of vascular inducible nitric oxide synthase mediates the hypotensive effect of ethanol in conscious female rats. J Appl Physiol 100, 1011-1018. 

      63.  El-Mas MM, Sharabi FM, El-gowilly SM and Mohy El-Din MM (2007). Inhibition of nitric oxide-guanylate cyclase-dependent and -independent signaling contributes to impairment of β-adrenergic vasorelaxations by cyclosporine. Biochemical Pharmacol 73, 359-367.

     64. El-Mas MM and Abdel-Rahman AA (2007). Intermittent clonidine regimen abolishes tolerance to its antihypertensive effect: a spectral study. J Cardiovasc Pharmacol 49, 174-181.

      65. El-Mas MM and Abdel-Rahman AA (2007). Role of myocardial contractility and autonomic control in the hypotensive response to a limited access ethanol paradigm in SHRs. Alcohol Clin Exp Res 31, 1071-1079.



(B) Abstracts
1. Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A and Zeitoun R (1985). Effects of andursil, ranitidine and prostaglandin E2 on indomethacin induced gastric ulcers in the rat. Annual Conference of the Egyptian Society of Pharmacology and Experimental Therapeutics, Alexandria, Egypt.
2. Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A. and Zeitoun R (1985). Protective effect of hyoscine against stress and indomethacin induced gastric ulcers in the rat. Egyptian Society of Pharmacology and Experimental Therapeutics, Alexandria, Egypt.
3. Rashida Z, Abou Zeit-Har MS, Bistawroos AE, El-Mas MM and Ghazal A (1985). Synergistic effect of combined antacid and ranitidine treatment on restraint induced gastric ulcers in the rat. Egyptian Society of Pharmacology and Experimental Therapeutics, Alexandria, Egypt.
4. El-Mas M and Hughes IE (1989). Differential effect of cocaine on electrically evoked tritium overflow from mouse vas deferens and rat brain cortical slices. Br J Pharmacol 98, 656P.
5. El-Mas M and Hughes IE (1990). Influence of cocaine on electrically evoked [3H]-NA overflow from noradrenergic nerves: tissue dependent effect. Br J Pharmacol, 99, 178P.
6. El-Mas M and Hughes IE (1991). Effect of cocaine on 3H-overflow evoked by different types of electrical stimulation of vas deferens loaded with 3H-noradrenaline. Fundam Clin Pharmacol 5: 461.
7. El-Mas MM and Abdel-Rahman A-RA (1992). Selective involvement of NMDA receptors in ethanol-induced attenuation of baroreflexes. Pharmacologist, 34, 167.
8. Abdel-Rahman A-RA, Carroll RG and El-Mas MM (1992). Ethanol reverses clonidine evoked decreases in plasma norepinephrine and arterial pressure in conscious rats. 7th International Catecholamine Symposium, Amsterdam, Abstr. 1.
9. El-Mas MM, Carroll RG and Abdel-Rahman AA (1993). Role of cardiac output in blood pressure normalization in carotid barodenervated rats. XXXII Congress of the International Union of Physiological Sciences, Glasgow, 172.14/P.
10. Fahim M, El-Mas MM, Abdel-Rahman AA and Moustafa SJ (1993). Diminished arterial smooth muscle response to adenosine analog in aortic baroreceptor denervated rats. XXXII Congress of the International Union of Physiological Sciences, Glasgow, 249.87/P.
11. El-Mas MM (1994). Interaction of anesthesia with baroreflex chronotropic responses: sex related effects. Annual Conference of the Egyptian Society of Pharmacology and Experimental Therapeutics, Cairo, Egypt, pp. 8.
12. Sharabi FM, El-Mallah AI, Omar AG and El-Mas MM (1996). Dopamine modulates neurotransmission at periphery through multiple presynaptic receptors: tissue-dependent effects. FASEB J 10 (3), Abstract#2467, pp. A427.
13. Abdel-Rahman AA and El-Mas MM (1997). Upregulation of brainstem imidazole receptors accounts for the enhanced hypotensive effect of clonidine in aortic denervated rats. Fundam Clin Pharmacol 11 (Suppl 1), 124s-125s.
14. El-Mas MM and Abdel-Rahman AA (1997). Contrasting effects of anesthetics on ethanol-clonidine hemodynamic interaction. FASEB J 11 (3), Abstract#2694, pp. A466.
15. Vadlamudi S, Cortright RN, El-Mas MM, Abdel-Rahman AA, and Barakat H (1998). Chronic alcohol feeding differentially alters insulin sensitivity in skeletal muscle and adipocytes in SHRs: Minisymposium. FASEB J 12 (4), Abstract#2058, pp. A354.
16. Abdel-Rahman AA, Mohamed MK, and El-Mas MM (1998). Estrogen enhancement of baroreflex sensitivity is centrally mediated. FASEB J 12 (4), Abstract#2316, pp. A398.
17. El-Mas MM and Abdel-Rahman AA (1998). Ovariectomy abolishes ethanol-induced impairment of baroreflex control of heart rate in conscious rats. FASEB J 12 (4), Abstract#2317, pp. A399.
18. El-Mas MM and Abdel-Rahman AA (1998). Role of the sympathetic control of vascular resistance in the differential effect of ethanol on I1-imidazoline and a2-adrenergic receptor evoked hypotension. Circulation 98 (17), Abstract#2349, pp. I-447.
19. El-Mas MM and Abdel-Rahman AA (1999). Radiotelemetric evaluation of the hemodynamic effects of long-term ethanol feeding in spontaneously hypertensive and wistar kyoto rats. FASEB J 13 (5), Abstract#128.24, pp. A115.
20. El-Mas MM and Abdel-Rahman AA (1999). Estrogen-dependent hypotensive and sympathoinhibitory effects of ethanol in conscious female rats. FASEB J 13 (5), Abstract#788.7, pp. A1045.
21. El-Mas MM and Abdel-Rahman AA (1999). Downregulation of a2-adrenoceptors in the nucleus tractus solitarius chronic ethanol feeding contributes to its hemodynamic interaction with a-methyldopa in telemetered spontaneously hypertensive rats. Experimental Biology meeting, Late-Breaking Abstract# 19.
22. Rekik M, El-Mas MM, Abdel-Rahman AA, and Mustafa SJ (2000). Long-term ethanol feeding enhances the vasorelaxing effect of adenosine in isolated aorta from spontaneously hypertensive rats. FASEB J 14 (4), Abstract#330-12, pp. A462.
23. Abdel-Rahman AA, El-Mas MM (2001). Evidence for the involvement of central I1-imidazoline receptor in ethanol counteraction of clonidine hypotension in SHRs. FASEB J 15 (4), Abstract#202.15, pp. A212.
24. El-Mas MM, Afify EA, Omar AG, Mohy El-Din MM, and Sharabi FM (2003). Testosterone reverses cyclosporine-induced chronic impairment of acetylcholine renovascular relaxations. FASEB J 17 (4), Abstract#386.8, pp. A617.
25. El-Mas MM and Abdel-Rahman AA (2003). Effects of chronic ethanol feeding on clonidine-evoked reductions in blood pressure, heart rate, and their variability: Time-domain analyses. FASEB J 17 (4), Abstract#400.3, pp. A651.
26. El-Mas MM, Mohy El-Din MM, El-Gowelli S and Sharabi FM (2003). Roles of endothelial relaxing factors in cyclosporine-induced inhibition of cholinergic and β-adrenergic renovascular relaxations. FASEB J 17 (4), Abstract#148.4, pp. A224.
27. El-Mas MM and Abdel-Rahman AA (2004). Age-related alterations in circadian hemodynamic rhythms in telemetered wistar-kyoto and spontaneously hypertensive rats. FASEB J 18 (4), Abstract#404.12, pp. A601.
28. El-Mas MM and Abdel-Rahman AA (2004). Chronic ethanol attenuates I1- or α2-receptor-mediated reductions in blood pressure and hemodynamic variability in hypertensive rats. FASEB J 18 (4), Abstract#404.13, pp. A601.
29. El-Mas MM and Abdel-Rahman AA (2004). Effects of long-term ovariectomy and estrogen replacement on clonidine-evoked reductions in blood pressure and hemodynamic variability. FASEB J 18 (4), Abstract#404.14, pp. A601-602.
30. El-Mas MM, Mohy El-Din MM, El-Gowelli S and Sharabi FM (2004). Regional and endothelial differences in the cyclosporine attenuation of adenosine receptor-mediated vasorelaxations. FASEB J 18 (5), Abstract#643.7, pp. A982-983.
31. El-Mas MM and Abdel-Rahman AA (2005). Intermittent clonidine regimen abolishes tolerance to its antihypertensive effect: a spectral study. FASEB J 19 (4), Abstract# 87.4, pp. A101.
32. El-Mas MM and Abdel-Rahman AA (2005). Autonomic modulation of altered diurnal hemodynamic profiles in ethanol-fed hypertensive rats. FASEB J 19 (4), Abstract# 87.5, pp. A101.
33. El-Mas MM, Zhang J and Abdel-Rahman AA (2005). Upregulation of vascular inducible nitric oxide synthase mediates the hypotensive effect of ethanol in conscious female rats. FASEB J 19 (4), Abstract# 87.6, pp. A101-102.
34. El-Mas MM and Abdel-Rahman AA (2005). Receptor specificity of the negative impact of ethanol on centrally-evoked hypotension in female rats. FASEB J 19 (4), Abstract# 87.7, pp. A102.

35.El-Mas MM, Mohy El-Din MM, El-Gowelli S and Sharabi FM (2006). Signaling mechanisms of cyclosporine-induced impairment of β-adrenergic vasorelaxations. BioVision Alexandria, Abstract# 37, pp. 17.

Email: mahelm@hotmail.com

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