| Prof. Dr. Ibrahim Labouta | |
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Date of Birth: July 19, 1948 Education: 1. B. Pharm. Sci., Faculty of pharmacy, University of Alexandria, June 1972 2. M. Pharm. Sci., Faculty of Pharmacy, University of Alexandria, August 1975 3. Ph.D, Faculty of Pharmacy, University of Alexandria, December 1978 4. Diploma of Higher Studies in Biochemical analysis, Faculty of Pharmacy, University of Alexandria, December 1989 5. A post - doctoral fellowship for two years (1980-1982), at Royal Danish School of Pharmacy, Copenhagen, Denmark. 6. An award for research encouragement in the field of Pharm. Sci, offered by Alexandria University 1983 Positions Held: 1. Teaching assistant, Pharm. Chem. Dept., Faculty of Pharmacy, University of Alexandria. 1972 - 1978 2. Assistant Professor, Pharm. Chem. Dept. Faculty of Pharmacy, University of Alexandria. 1984 – 1989 3. Associate Professor, Pharm. Chem. Dept., Faculty of Pharmacy, University of Alexandria 1984 - 1989 4. Professor, Pharm. Chem. Dept., Faculty of Pharmacy, University of Alexandria 1989 - Present 5. WHO/EMRO consultant (Chief Technical Division) in Iraq under Oil For Food Programme since March 1998- Nov.2003. 6. Chairman , Pharm. Chem. Dept., Faculty of Pharmacy, University of Alexandria Aug 2005 - Present Experience: I. Consultancies: 1. Assigned to WHO office/ Iraq on 31st March 1998 until Nov. 2003 under Security Council Resolution 986 to participate in implementing the observation plan for MOU drugs as required; to participate in developing a proper methodology for drugs needs assessment; to assist in improving drug supply system. Since June 1999, upon the request of WHO/EMRO, assigned to assist in coordinating and monitoring of SCR 986 programme execution which includes collecting and analyzing specific information pertaining to the distribution of health commodities, development of health and health related programmes; to organize the generation and smooth flow of information and implementing reporting systems relevant to observation process and other routine and ad hoc report; to provide technical support to the pharmaceutical supply system in the three northern governorates; to assist in supervising and coordinating the functions of technical operations divisions and staff attached to these divisions (more than 25); and performing other duties assigned by WR/Iraq. 2. Assigned to WHO office of Syria to act as a team leader of WHO Iraq team in Syria during the evacuation, March 2003. 3. Assigned to WHO/EMRO office to assist in finalization of 90 Day Emergency Plan for Iraq 11 – 24 May 2003. 4. Assigned by EMRO to visit New York from 16th to 24th March, 2002 according to the terms of reference listed below: • To accompany WHO team to meetings with officials of the Office of Iraqi Programme (OIP) and the sanction committee 661. • To provide technical assistance related to the above meetings. 5. Assigned to WHO Representative – Jordan from 16 – 17 October 2003, to: • Review the emergency health plan influx of Iraqi refuges • Assess drugs needs of the expected internal displacements • Assess the technical support to be provided to WRO – Jordan 6. Assigned to WHO office, Afghanistan from 26 July to 8 September 1991 to review the procedure for chemical analysis at Central Quality Control Laboratory; to train nationals on chemical analysis of drugs; to conduct training courses on chemical quality control. 7. Assigned by WHO/EMRO to participate in the technical briefing seminar that took place in WHO/HQ (Geneva) in October 2003. 8. Assigned to WHO/EMRO to assist in the translation of the several of WHO publications into Arabic such as Managing Drug Supply, Guide to Good Prescribing, New emergency health kit etc. 9. Assigned to WHO/EMRO to participate in the following Inter-country meetings: - The role of clinical pharmacology in medical and pharmacy curricula in Ismailia, Egypt, 19- 21 November 1993. The applicant has prepared the final technical report. - Bio-availability and Bio-equivalence in Alexandria, Egypt 1993 10. Assigned to WHO/EMRO to translate several of WHO publication into Arabic (Managing Drug Supply, Guide to Good Prescribing, New Emergency Health Kit etc) II. Academic Experience 1. Teaching: more than 25 years teaching experiences for undergraduate and graduate students in several universities in Egypt, Lebanon, Ethiopia, Jordan and Denmark, and supervised 6 master and PhD thesis. 2. Publications: The applicant has published 37 research articles in international specialized journals in the area of drug design of anti-cancer, antihistaminic, contraceptive etc... List of Publications: 1-Synthesis of Benzimidazole Derivatives with Potential Antihistaminic Activity. S.M.Rida, S.A. Shams EL-Dine and I.M.Labouta. Die Pharmazie 32, 577(1977).
2.Synthesis of 5, 6 Diaryl-1,2,4-Triazines. El-Sebai A. Ibrahim, S.A. shams El-Dine, Farid S.G.Soliman and Ibrahim M. Labouta Z. Naturforsch. 33b, 1503 (1978).
3. Potential Antineoplastics: Part I: 6-Substituted -3,5-dioxo and -3-Thioxo -2,3,4,5-tetrahydro -1,2,4- Triazines El-Sebai A. Ibrahim, S.A. Shams El-Dine, Farid S.G. Soliman and Ibrahim M. Labouta J.Pharm. Sci. 68, 243 (1979).
4.Potential Antineoplastics: Part 2: New Thiazolo - [1,2,4] - triazine Derivatives. El-Sebai A. Ibrahim, S.A. Shams El-Dine, Farid S.G. Soliman and Ibrahim M. Labouta Die Pharmazie 34, 392 (1979).
5. Synthesis and Antihypertensive Properties of a Novel Series of 3-Substituted Amino-S-triazolo- [3,4-a] phathalazine Derivatives. A. Mohsen M.E.Omar, M. Gabr Kassem, I.M. Iabouta and J.Bourdais. J. Heterocycl. Chem. 18, 499 (1981).
6. GABA Uptake Inhibitors as Experimental Tools and Potential Drugs in epilepsy Research. P. Krogsgaard-Larsen, I.M. Labouta, B.Meldrum, M. Groucher and A. Schousboe (1981): In: Neurotransmitters, Seizures and Epilepsy, edited by P.L. Moreselli, K.G. Lioyd, W.Loscher, B. Meldrum, E.B. Reynolds. PP. 23-33 Raven Press, New York.
7. Polysubstituted Pyrazoles: Part 3: New O- and C-Allyl Derivatives of 4-hydroxypyrazoles of Possible Biological Interest. Farid S.G. Soliman and Ibrahim M.Labouta Die Pharmazie 37, 170(1982).
8. Synthesis of Some Cyclic Amino Acids Structurally Related to the GABA Analogue Home-B-proline. Ibrahim M.Labouta, Poul Jacobsen, Pia Thorbek, Povl Krogsgaard-Larsen and Hans Hjeds. Acta. Chem. Scand. B36, 669 (1982).
9. Cyclic GABA analogues: Synthesis and Structure-activity Studies of 4-Piperidinacetic acid and Related Compounds. Ibrahim M.Labouta, Erik Falch, Hans Hjeds, and Povl Krogsgaard-Larsen. Eur.J.Med.Chem. 17, 531(1982).
10. Hydroxy-and Amino-Substituted Piperdinecarboxylic Acid as g- Aminobutyric Acid Agonists and uptake Inhibitors. Poul Jacobsen, Ibrahim M. Labouta, kjeld Schoumburg, Erik Flack and Povl krogsgaard-Larsen. J.Med. Chem. 25, 11 57(1982).
11. Synthesis of Some Triazoly-thiourea Derivatives as Potential Antimicrobial Agents. Aly A. Hazzaa, Ibrahim M.Labouta and M.Gabr Kassem. Arch. Pharm. Chem. 11,43(1983).
12. Arylidenepyruvic Acid Thiosemicarbazone and Thiazoline Derivatives as Potential Antimicrobial Agents. A. Mohsen M.E. Omar, Ibrahim M.Labouta, M.Gabr Kassem and J.Bourdais. J.Pharm. Sci. 72, 1226(1983).
13. Reactions of some Coumarins with Hydrazine and Phenylhydrazine. F.S.G. Soliman, I.M.Iabouta and W.Stadlbauer. Arch. Pharm.Chem. 13, 49 (1985).
14. Synthesis of Some 3-(Benzimidazol-2-ylmethyl) thiazolidinone Derivatives as Potential Antimicrobial Agents. Samia M. Rida, Hassan M.Salama, Ibrahim M. Labouta and Yasser S.A.Ghany. Die Pharmazie 40, 727(1985).
15. Synthesis and In vitro Antimicrobial Activities of Thiazolo-[3,2-a] benzimidazol-3(2H)-ones. Samia M. Rida, Hassan M.Salama, Ibrahim M.Labouta and Yasser S.A.Ghany. Die Pharmazie 41, 324(1986).
16. Synthesis and In vitro Antimicrobial Evaluation of Some Benzimidazol-2-ylmethyl Thioureas, Benzimidazol-2-ylacetylthiosemicarbzides and Products of their condensation with Monochloroacetic Acid. Samia M. Rida, Ibrahim M.Labouta, H.M.Salama, Yasser S.A.Ghany, E.El-Ghazzaui and O.Kader. Die Pharmazie 41, 475 (1986).
17. Synthesis and In vitro Antimicrobial Evaluation of Some 5 Substituted-3-phenacyl Thiazolidine-2,4-diones. Hassan M. Salama, Ibrahim M. Labouta and Mohamed A. Mostafa. 1st IBNSINA SYMPOSIUM ON HETEROCYCLIC CHEMISTRY, Cairo 10-12/ 12/1986. Alex. J. Pharm. 4, 44(1990)
18. Some Substituted Imidazo [1,2,4] triazines and 8H-Pyrimido [1,2-b] [1,2,4] triazin-8-ones as Potential Antineoplastic Agents. Ibrahim M.Labouta, Farid S.G.Soliman and Mohamed G.Kassem. Die Pharmazie 41, 812(1986).
19. Potential Antimicrobial: Synthesis and In vitro Antimicrobial Evaluation of Some 5-Arylazo-thiazolidones and Related Compounds. Ibrahim M. Labouta, Hassan M. Salama, Nabil H. Eshba, O. Kader and E. El-Cherbini. Eur. J.Med. Chem. 22,485(1987).
20. Potential Antineoplastics: Some Substituted Imidazo [1,2-b] [1,2,4] triazines, Triazino [4,3-b] [1,2,4] triazins and Imidazotriazino [5,6 -b] indoles. Ibrahim M. Labouta, Nabil H. Eshba and Hassan M. Salama. J.Serb.Chem.Soc. 52 , 523(1987).
21. Synthesis of Some Substituted -1,2,4-triazino [5,6-b] indole Derivatives as Potential Antiviral and Anticancer Agents. Nabil h. Eshba, Hassan M.Salama, Ibrahim M.Labouta and A.M.E.Omar. Die Pharmazie 42,664(1987).
22. Synthesis and Biological Activity of GABA Agonist Which Has No Effect On Benzodiazepine Binding and of Structurally Related Glycine Antagonists. Jette R. Byberg, Ibrahim M.Labouta, Erik Falch, Hans Hjeds, Povl Krogsgaard-Larsen, David R. Curtis and Bruce D.Gynther. Drug Design and Delivery 1, 261-74(1987)
23. Synthesis of Some Substituted Triazolo [4,3-b][1,2,4] triazines as Potential Anticancer Agents. Ibrahim M. Labouta, Nabil H.Eshb and Hassan M.Salama. Monatsh. Chem. 119,591(1988).
24. Potential Antineoplastics: Synthesis and Anticancer Evaluation of Some Substituted 1,2,4- Triazines. Ibrahim M. Labouta, Nabil H. Eshba, and Hassan M.Salama. FARMACI 16, 29(1988).
25. Novel Indolinones with Potential Antimicrobial and Antineoplastics Activities. Ibrahim M.Labouta, Hassan M.Salama, Nabil H. Eshba and Eglal El-Sherbini. Acta Pharm. Jug. 38, 198(1988).
26. Synthesis and Evaluation of Some 4-Aryl-1- [2-( substituted thiocarbamoylhydrazino) propyl] thio [1,2,4] triazolo [4,3-a] quinazolin-5(4H)- ones for Potential Antimicrobial Activity. A. Mohsen M.E.Omar, S.A.Shams El-Dine, Ibrahim M.Labouta and Alaa A.M.El-Tombary. Alex. J.Pharm. Sci. 11 176 (1988).
27. Synthesis and Evaluation for Antimicrobial and Antihistaminic Properties of New Thiosemicarbazide and Triazole Derivatives of Triazolo [4,3-a] quinazolin-5(4H)-ones. A. Mohsen M.E. Omar, S.A.Shams El-Dine, Ibrahim M.Labouta and Alaa A.M.El-Tombary. 1st ANGLO-EGYPTIAN CONFERENCE OF PHARMACEUTICAL SCIENCES. ALEX.J.Pharm. Sci . 5, 313(1991).
28. Synthesis of Some Substituted Benzimidazoles, with Potential Antimicrobial Activity. Ibrahim M. Labouta, Ahmed M.Hassan, Omaima M.Aboulwafa and Ola Kader. Montash.Chem, 120,571 (1989).
29. Novel 1,2,4-Triazolo [4,3-a] quinazolinones as Potential Antimicrobial Agents. A. Mohsen M.E.Omar, S.A. Shams El-Dine, Ibrahim M.Labouta and Alaa A.M.El-Tombary. Alx.J.Pharm. Sci. 5,941(1991).
30. Synthesis and Antimicrobial Activities of 4-Substituted Benzyl piperazines. Mohamed A. Hassan, Ibrahim M.Labouta and Mohamed Y.Toumeh. First international East Conference on Pharmaceutical Science, Irbid, Jordan May 3-5(1993.
31. Potential Antineoplastics: Synthesis and Biological Evaluation of some Substituted -1,3,4-thiadiazolo [2,3-c] [1,2,4] triazines. Ibrahim M.Labouta. First International East Conference on Pharmaceutical Science, Irbid, Jordan May 3-5(1993).
32 . Synthesis, Estrogen Receptor Binding Affinity and Biological Evaluation of Some 2-Thiazolylestone and Estratrieno [17,16-d] thiazole Derivatives. A. Mohsen M. E. Omar,Omaima M. Aboulwafa,Ibrahim M. Labouta, Alaa A. EL-Tombary andAhmed I. EL-Mallah Alex. J. Pharm. Sci. 10,19 (1996 )
33 . 4`,17-Dioxo-5`H-estra-1(10),4-dieno[3,2-b]furan:Synthesis, Binding Affinity to the Estrogen Receptor, Uterotrophic and Antiimplantation Activities A.Mohsen M. E. Omar, Omaima M. Aboulwafa, Ibrahim M. Labouta, Alaa A. EL-Tombary, Ahmed I. Mallah. Arch. Pharm. Pharm. Med. Chem. 329,61(1996).
34 . Synthesis, Estrogen Receptor Binding Affinity And Biological Evaluation Of Some 2-Substituted Estrone Derivatives. A.Mohsen M. E. Omar, Omaima M. Aboulwafa, Ibrahim M. Labouta, Alaa A. EL- Tombary and Ahmed I. EL-Mallah. IL FARMACO .52 ,219, (1997)
35 .Synthesis and Biological Evaluation Of Some Isatine Schiff Bases and Their Copper, Cobalt and Nickel Complexes Ibrahim M. Labouta, M.M. El-Komi, M. F. Iskander, A. M. Walily, H. A. E. Hemaida and A.I. Beltagy 7th international Conference On Enviromnental Protection is a Must,20-22 May, 1997, Alexandria, Egypt.
36. Synthesis Of Some 4-Benzyl-1-Substituted Piperazine Derivatives As Potential Antimicrobial and Anticancer Agents. Mohamad A. Hassan, Mohammad T. Youssef, Ahmad S. Alkofahi, Hani D. Tabba and Ibrahim M. Labouta Acta Pharmaceutica Turcica, 40, 53-57 (1998)
37. Pharmacy Practice and IT: A Case of E-Hospital Ibrahim M. Labouta and N. Nabil FIP Cairo, 103, (2005) Mailing Address: 8 Loa Yousry Kamha Str., Gleem, Alexandria Egypt Email: laboutai@yahoo.com Telephone: 203-5844729 |
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